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The liquid biopsy-based multi-cancer early detection test to recieve CE Mark and Breakthrough Device Designation from both the FDA and the NMPA.
OverC® covers 70.000+ methylated loci to enable early detection of esophageal, lung, liver, pancreatic, and ovarian cancer.
Key Features and Benefits

One tube of blood for precise early detection of 6 cancer types




Recommended for Adults Aged 50-75

OverC® is not suitable for people who have acute infection/inflammation within 14 days, or have recently used anti-tumor drugs, or have a hemorrhagic disorder.

Note: The FDA Breakthrough Device Designation for OverC applies to five cancer types: esophageal, lung, liver, pancreatic, and ovarian, and does not include colorectal cancer


Performance Validations
Clinical Trial Studies

THUNDER Study


● Multi-cancer detection blood test-1 (MCDBT-1) had a sensitivity of 69.1% and a specificity of 98.9% in detecting six cancers.


● MCDBT-1 decreased cancer late-stage incidence by 38.7%‒46.4% and increased 5-year survival rate by 33.1%‒40.4%.

● In parallel, MCDBT-2 was set at a lower specificity but a higher sensitivity than MCDBT-1.




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Biomarker Discovery & Translational Research
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