Key Features and Benefits
Performance Validations





Accuracy
224 clinical tumor plasma samples and cell line samples
SNV: PPA> 98.0%, Indel/Fusion/CNV/MSI: PPA=100.0%
Specificity
130 healthy human plasma samples and cell line samples
SNV: NPA by sample= 95.3% and NPA by site>99.9%
Indel/Fusion/CNV/MSI: NPA=100.0%
Biomarker Panels
AKTI
ALK*/**
APC
AR
ARID1A
ATM
ATR
B2M
BARD1
BRAF
BRCA1
BRCA2
CCNDI**
CD274
CD74*
CDK4**
CDK6**
CDKN1A
CDKN1B
CDKN2A
CHEK2
CTNNB1
EGFR**
ERBB2**
FRBB3
ERBB4
ESR1
FANCA
FANCI
FAT3
FBXW7
FGF19
FGF3
FGF4
FGFR1*/**
FGFR2*/**
FGFR3*/**
FLT1
FLT3
FLT4
GATA3
HRAS
IDH1
IDH2
JAK1
JAK2
KDA
KEAP1
KIT
KMT2D
KRAS**
MAP2K1
MET**
MLH1
MRE11
MSH2
MSH6
MTOR
MYC**
MYCN
NBV
NF1
NFE2L2
NOTCH1
NRAS
NTRK1*
NTRK2
NTRK3*
PALB2
PDGFRA
PDGFRB
PIK3CA
PIK3CG
PIK3R1
PMS2
POLD1
POLE
PTEN
RAD50
RAD51B
RAD51C
RAD51D
RAD54L
RAF1
RARA
RB1
RET*
RNF43
ROS1
SDC4*
SMAD4
SMARCA4
STK11
TERT
TP53
TP63
VEGFA
VEGFB
VEGFC
VHL
YES1*


* Genes for fusion detection

** Genes for CNV (amplification) detection

Specifications
Certification
CE-IVD
Tests/Kit
24
Alteration detected
SNV, InDel, CNV, Fusion and MSI
Sample type
Tumor Plasma Samples
Sequencing Type
PE150
Sequencer
Illumina Nextseq500/550Dx
Contact Our Biopharma Team to Learn More
Biomarker Discovery & Translational Research
Clinical Trial Design & Patient Recruitment
Global Capabilities for Clinical Studies
CDx Development & Commercialization
Genomic Data Solutions
ctDNA Monitoring Portfolio
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